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原发性肝癌根治切除后肝动脉和/或门静脉插管化疗预防肝癌复发

HAI and/or PVI after radical resection of primary hepatic carcinoma for preventing tumor recurrence

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【作者】 何友钊郝计虎李美荣

【Author】 HE You-zhao1, HAO Ji-hu2, LI Mei-rong3 (1.Department of Hepatobiliary and pancrease surgery. The Third People’s Hopital of Wuxi City, Wuxi, Jiangsu 214041, China; 2.Hospital of Xishan City, Xishan, Jiangsu 214171, China; 3.The People’s Hospital of Gaozho

【机构】 江苏省无锡市第三人民医院肝胆外科!江苏无锡214041江苏省锡山市口腔医院!江苏锡山214171广东省高州市人民医院!广东高州525200

【摘要】 目的 探讨原发性肝癌根治切除后肝动脉和 /或门静脉插管皮下药物泵对肝癌复发的预防效果。方法 回顾性分析 1995年 6月~ 2 0 0 0年 4月根治性切除的原发性肝癌患者 49例 ,其中并行肝动脉和门静脉插管 12例 (I组 ) ,单纯肝动脉插管 8例 (II组 ) ,单纯门静脉插管 15例 (III组 ) ,14例未插管 (IV组 )。随访 6个月~ 5年 ,对结果进行比较。结果 I ,II ,III组 1年复发率低于IV组 ,1年生存率各组间无差异 ;I ,II组 3年复发率低于IV组 ,3年生存率也高于IV组 ,而 5年复发率与生存率无差异。I ,II ,III组比较 1,3,5年复发率与生存率无明显差异。结论 原发性肝癌术后行肝动脉和 /或门静脉插管皮下置药物泵简便 ,安全 ,是预防肝癌复发的有效手段。

【Abstract】 Objective To study the effect of HAI and/or PVI after radical resection of hepatocellular carcinoma (HCC) for preventing recurrence.Methods From Jun. 1995 to Apr. 2000, 49 patients with HCC were undergone radical tumor resection. They were divided into 4 group: the treatment combined with HAI and PVI was given in group I(12 cases), HAV alone in group II (8 cases); PVI alone in group III (15 cases); nothing in group IV (14 cases). All patients were followed up for 6 months to 5 years. Results Recurrence rate at one year didn’t show significantly lower in group I, II and III than that in grou IV. Survival rate in one year showed no significant difference in 4 groups. Recurrence rate in three years was significantly lower in group I and II than that in group IV. Survival rate in three years was significantly higher in group I and II than that in group IV. Recurrence rate and survival rate in five years showed no significante difference in four groups. Conclusions The treatment of radical resection of HCC combined with HAI and/or PVI is simple and safe. It is an useful method for preventing tumor recurrence.

  • 【文献出处】 中国普通外科杂志 ,Chinese Journal of General Surgery , 编辑部邮箱 ,2001年02期
  • 【分类号】R735.7
  • 【被引频次】4
  • 【下载频次】49
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