【摘要】 目的　观察烯萜醇对大鼠胃腺癌的治疗作用 .方法　经饮水摄入N 甲基 N′ 亚硝基 N 亚硝基胍(MNNG ,15 0mg/L)诱发大鼠胃腺癌 ,同时食烯萜醇添加食进行治疗 .结果　食烯萜醇添加食 2 0g/kg ,10 g/kg ,32周大鼠胃腺发生原位癌、浸润癌 ,胃癌发生率分别为 11.5 % ,2 2 .6 % ,平均癌巢数分别为 0 .12± 0 .5 8,0 .8±0 75 ,与对照组比较具有显著差异 (P <0 .0 1或P <0 .0 5 ) ,且与给药剂量密切相关 .结论　烯萜醇具有抑制大鼠胃腺癌的作用 .更多还原

【Abstract】 Objective The experiment is to observe the effect of Xi Tie alcohol on adenocarcinoma of stomach in rats.Methods MNNG 150mg/L was taken in through drinking water to induce adenocarcinoma of stomach in rats.At the same time,the rats were added food with Xi Tie alcohol.Results With Xi Tie alcohol 20g/kg,10g/kg was taken in, and in 32 weeks the incidence of carcinoma in situ,infiltrative carcinoma and carcinoma of stomach in the gastric glands of rats were 11.5% and 22.6% respectively,the number of cancer nests in average was 0.12±0.58 and 0.80±0.75 respectively,and showed significant difference with the control group(P<0.01 or P<0.05),also closely correlated with the dose of drug administration.Conclusion Xi Tie Alcohol exhibit the effect of inhibiting adenocarcinoma of stomach in rats.更多还原