【摘要】 目的 :评价乳腺癌脑转移 3种治疗方法 (放疗、化疗、放化疗 )的疗效及其预后因素分析。方法 :放疗2 0例、化疗 11例、放化疗 32例。结果 :放疗组、化疗组和放化疗组的有效率分别为 30 %、2 7.3%、5 9.4%;中位生存期分别为 6 .2月、5 .7月、8.9月 ;1年生存率分别为 35 %、36 .4%、5 9.4%。放化疗组的疗效明显优于放疗组及化疗组 (P<0 .0 5 ) ;而放疗组疗效与化疗组的疗效之间无显著性差异 (P>0 .0 5 )。结论 :放化疗是治疗乳腺癌脑转移较有效的治疗方案更多还原

【Abstract】 Objective:To evaluate the efficacy and the prognosis of 63 cases of breast cancer with brain metastasis.Methods:63 cases of breast cancer with brain metastsis were divided into three groups:① 20 patients with radiotherapy alone;② 11 patients with chemotherapy alone;③ 32 patients with radiotherapy plus chemotherapy.Result:The response rates of the three groups were 30%,27.3% and 54.4% respectively,the median survival periods of three groups were 6.2 months,5.7 months and 8.9 months respectively,the 1 year survival rates of three groups were 35%,36.4% and 59.4% respectively.This study shows that the curative effect of radiotherapy plus chemotherapy is much better than that of radiotherapy and chemotherapy alone( P <0.05),but without statistical difference between radiotherapy and chemotherapy ( P >0.05).Conclusion:Radiotherapy plus chemotherapy can be considered as a better regimen for breast cancer with brain metastasis.更多还原