节点文献

射频消融术中术后血凝状态改变的观察

Observation on the changes of the blood coagulable states during and after radiofrequency catheter ablation

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 李建平黎莉张薇潘秀荣梁绪国

【Author】 LI Jianping, LI Li, ZHANG Wei, et al Division of Cardiology, Yantaishan Hospital, 264001

【机构】 烟台市烟台山医院心内科山东医科大学附属医院心内科烟台毓璜顶医院心内科

【摘要】 目的 通过对射频消融 (RFCA)术中术后D 二聚体 (DD)浓度及血小板α颗粒膜糖蛋白(GMP 140 )表达变化的观察 ,研究RFCA对血凝状态的影响。方法 对连续 32例接受RFCA治疗的病人 ,在插管前、电生理标测完成 ,放电前、放电后及术后 40~ 48h ,动态测定血浆DD浓度及GMP 140阳性表达活化血小板百分率。结果 平均血浆DD浓度及活化血小板百分率 ,在插管前分别为 :5 5 8±2 85 ;1 6 5 2± 0 918,电生理标测后为 :984± 5 2 6 ;3 12 1± 2 76 5 ,放电后为 :1879± 892 ;4 135± 3 6 0 9,术后40~ 48h分别为 :90 7± 491;5 2 43± 3 5 96。各组与基线值比较 ,均明显增高。结论 RFCA术中、术后血浆DD浓度增高 ;GMP 140表达增加 ,RFCA造成血凝状态改变。

【Abstract】 Objective To investigate whether the application of radiofrequency energy might activate endogenous thrombotic mechanisms and platelets, whether radiofrequency catheter ablation (RFCA) might result in changes of the blood coagulable states Methods We made serial determinations of plasma D dimer level by enzyme immunoassay and the percentage of activated platelet with positive exepression of GMP 140 by flow cytomety before insertion of catheters,after completion of electrophysiologic study (EPS) but before RFCA, immediately after RFCA, and 40~48 h after RFCA in 32 consecutive patients undergoing RFCA Results The mean D dimer level was 558±285 (μg/L); 984±526; 1879±892; 907±491,respectively The mean percentage of activated platelet with positive exepression of GMP 140 was 1 652±0 918 (%); 3 121±2 765; 4 135±3 609; 5 243±3 596, respectively Conclusion As reflected by elevated plasma D dimer level and platelet activated percentage RFCA might result in changes of the blood coagulable states

  • 【文献出处】 中国介入心脏病学杂志 ,Chinese Journal of Interventional Cardiology , 编辑部邮箱 ,2001年03期
  • 【分类号】R541.7
  • 【被引频次】2
  • 【下载频次】24
节点文献中: 

本文链接的文献网络图示:

本文的引文网络