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血清CA125水平与子宫内膜癌预后的关系

Relationship between serum CA125 level and prognosis in the patients with uterine endometrial carcinoma

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【作者】 谢志贤张京豫谭爱国艾桂萍

【Author】 XIE Zhixian, ZHANG Jingyu, TAN Aiguo, et al. Department of Clinical Laboratory, Beijing Hospital, Beijing 100730, China

【机构】 卫生部北京医院检验科卫生部北京医院检验科 100730100730

【摘要】 目的 探讨子宫内膜癌患者血清CA1 2 5水平与其预后的关系。方法 应用微粒子方法检测 71例子宫内膜癌患者血清CA1 2 5值 ,将 71例患者分别从手术 病理分期、组织类型、影响预后的其他因素等方面加以研究对比。结果 手术 病理分期越高CA1 2 5阳性率越高 ,且绝经后患者高于绝经前。CA1 2 5水平与组织类型有关。CA1 2 5水平与影响预后的其他因素有关。若术后CA1 2 5值升高 ,提示可能复发。结论 CA1 2 5水平对预测预后有参考价值。

【Abstract】 Objective To study the relationship between serum CA125 level and prognosis of uterine endometrial carcinoma. Methods The serum CA125 levels in 71 patients with uterine endometrial carcinoma were measured by using microparticle enzyme immunoassay. The relationship between preoperative CA125 levels and surgical pathologic staging, histologic classification, and other prognostic factors was investigated. Results (1) The positive rate of serum CA125 in postmenopausal patients was significantly higher than in premenopausal patients. (2) The positive rate of serum CA125 was related to surgical pathologic staging. (3) Serum CA125 level was correlated not only with histological classification but also with other prognosis factors. (4) Increase of serum CA125 after operation predicted the possibility of relapse. Conclusion CA125 is a useful marker in predicting the prognosis of uterine endometrial carcinoma.

【关键词】 子宫内膜肿瘤肿瘤标记生物学
【Key words】 Endometrial carcinomaCA125
  • 【文献出处】 中华医学杂志 ,National Medical Journal of China , 编辑部邮箱 ,2001年23期
  • 【分类号】R737.33
  • 【被引频次】7
  • 【下载频次】93
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