【摘要】 目的　研究增生性玻璃体视网膜病变 (proliferative vitreoretinopathy,PVR)的视网膜前膜(epiretinal membranes,ERM)中纤维连接蛋白 (fibronectin,FN)与整合素 β1 (β1 integrin,β1 )的表达。　方法　用免疫组织化学的方法对 2 0例 PVR患者行玻璃体切割术时剥离的 ERM进行观察。　结果　 FN与β1分别在 18例及 16例 ERM中过度表达。　结论　 ERM中有 FN及β1 的表达 ,提示二者在 PVR的发生发展中有一定作用。更多还原

【Abstract】 Objective To study the expression of the fibronectin (FN) and β 1 integrin (β 1) in epiretinal membranes(ERM) of eyes with proliferative vitreoretinopathy(PVR). Methods Twenty epiretinal membranes were obtained from eyes undergone vitrectomy for retinal detachment complicated with PVR and observed by immunohistochemical methods. Results Overexpression of FN and β 1 were observed in 18 and 16 membranes respectively. Conclusion The synergism of FN and β 1 in their action mignt be one of the important roles in the development of PVR.更多还原