【摘要】 目的探讨胃癌前病变的转归以及与胃癌的关系。方法收集分析 1988～ 1997年我院经胃镜及病理确诊的胃癌前病变患者 500例相关资料，进行 5～ 10年的胃镜跟踪随访。结果 (1)胃溃疡组 (GU)156例，经治疗总有效率为 84.6％，发生癌变 4例，检出率为 2.6％； (2)慢性萎缩性胃炎组 (CAG)300例，经治疗后，好转 98例，占 32.6％，无变化 131例，占 43.7％，不同程度加重 71例，占 23.7％，发生癌变 6例，检出率为 2％； (3)胃息肉组 44例，其中 2例为多发性息肉，均发生癌变，占 4.5％。结论确认为胃癌前病变的患者应积极治疗，可提高治愈率，但因种种原因，部分患者可加重，少数可癌变。因此采取长期胃镜跟踪随访是必要的、有效的措施。更多还原

【Abstract】 Objectives To study the changes of precancerous lesions of stomach and their relationship with gastric cancer. Methods To collect and analyse the relevant data of 500 patients with precancerous which were diagnosed by gastroendoscopy and a follow－ up gastroscopic study was done for 5 to 10 years between 1988 and 1997. Results 1.Of the 156 cases of gastric ulcer, the efficacy of treatment was 84.6％ ; there were 4 cases of canceration, with a detecting rate of 2.6％ . 2.Of the 300 cases of chronic atrophic gastritis,98 (32.6％ )patients improved after treatment, 132(43.7％ ) patients showed no improvement, and 71(23.7％ ) patients deteriorated, among them there were 6(2％ ) cases of canceration, 3.Among the 44 cases of gastric polyps,2(4.5％ ) cases of multiple polyps were detected and canceration appared in both cases. Conclusion The result suggested that patients diagnosed pathologically of precancerous changes should be rendered with active clinical treatment, and there would be higher rate of being cured. But for various reasons, some patients might deteriorate and few might develop cancer. Therefore, long－ term gastroscopy follow－ up is inevitable.更多还原