【摘要】 目的　评价99mTc甲氧基异丁基异腈 (MIBI)乳腺显像对乳腺癌诊断的价值。方法　对 195例 2 0 4处乳腺肿物患者分 3组进行99mTc MIBI显像 ,并与病理对照 ,另选择无乳腺疾病者 2 0例作对照组。99mTc MIBI在乳腺中有异常浓聚且阈值数大于健侧相对应区 10 %时为阳性。结果　本研究中乳腺癌病变 10 0处 ,阳性显像 92处 ;乳腺良性病变 70处 ,阳性显像 12处 ;隐匿性病变 34处 ,阳性显像 6处 ,3处为乳腺癌 ;对照组 2 0例显像均阴性。99mTc MIBI对乳腺疾病的诊断准确率为 92 0 %、灵敏度为 91 8%、特异度为 92 %、阳性预测值为 86 %、阴性预测值为 92 %。结论　 99mTc MIBI对乳腺癌的诊断及良恶性病变的鉴别有较高的敏感性和准确性。更多还原

【Abstract】 Objective To evaluate the clinical usefulness of 99m Tc MIBI imaging for the diagnosis of breast malignancy.Methods 195 patients with a total of 204 breast lesions were divided into three groups to undergo 99m Tc MIBI imaging and the results were compared with pathology.20 cases with normal breast served as control.Abnormal density showed by 99m Tc MIBI imaging in the breast(10% higher than surrounding structure) was regarded as positive.Results Of 100 breast cancer lesions,positive feature appeared in 92.Twelve out of 70 benign breast lesions showed positive imaging.Six out of 34 breast occult lesions were with positive imaging, among them 3 were finally found with carcinoma.No positive imaging was found in the control group.The diagnostic accuracy,sensitivity,specificity,positive predictive value,negative predictive value of 99m Tc MIBI was 92 0%,91 8%,92%,86%, and 92%,respectively.Conclusions[WT5”BZ] 99m Tc MIBI imaging has high sensitivity and accuracy in the diagnosis of breast cancer and in the differentiation between benign and malignant breast lesions.更多还原