【摘要】 目的　了解在人蛔虫和猪蛔虫感染并存的农村社区内因交叉感染发生的可能性 ,猪蛔虫对人群蛔虫感染传播的作用。方法　选择两个基线情况基本相同的自然村 ,即江西省新建县樵舍乡蔓湖行政村的老支村和畔支村为实验现场。在对两村所有人群进行相同药物治疗处理的同时 ,对其中 1个村的猪群也进行治疗 ,并以约 2个月的间隔重复对猪治疗 2次 ,但对另一村的猪群不作治疗处理。在随后 1年内 ,约每 2个月 1次 ,用改良加藤法观察两村人群蛔虫感染的回升情况。结果　药物治疗后连续 5次横断面调查表明 ,人群蛔虫流行率和感染度在两村之间均无统计学差异 (χ2 <0 .6 5 8,F <1.6 5 8,P >0 .1)。结论　当地猪蛔虫的传播对人群蛔虫的传播无重要影响更多还原

【Abstract】 Objective An experimental epidemiological study was designed to investigate possible relations of pig derived Ascaris to the transmission of human ascariasis which might be caused by cross infection between the pig and humans. Methods In Xinjian County, Jiangxi province, two adjacent villages, Laozhi and Panzhi, with similar baseline of ascariasis in pig and human populations were selected as the study sites with a one year longitudinal epidemiological follow up study. People in the two villages received mass chemotherapy. Pigs received mass chemotherapy only in Panzhi village and was twice repeated with two months interval, while pigs in Laozhi village were not treated at all. In the following year after treatment on humans, ascariasis among villagers was studied cross sectionally five times with Kato katz technique.Results No significant difference of the re infection patterns of human ascariasis was found between the two villages in terms of prevalence and intensity during the following year in all the five surveys (χ 2< 0.658 , F< 1.658 and P > 0.1 ).Conclusion The results suggested that pig derived Ascaris were mainly transmitted among pigs but had no important role on the transmission of human ascariasis. The results were in good accordance with the findings through a recent molecular genetic research on the local human and pig derived Ascaris worms. Possible confounding factors were discussed.更多还原