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肺良性病变18F-FDG符合线路SPECT显像

The manifestation of 18 F-FDG imaging of coincidence SPECT in benign pulmonary diseases

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【作者】 苗积生刘进军吴吉勇潘惠忠王火强沈毅史德刚

【Author】 MIAO Jisheng,LIU Jinjun,WU Jiyong,et al.Shanghai Pneumology Hospital,Shanghai 200433,China

【机构】 上海市肺科医院核医学科复旦大学医学院华山医院核医学科

【摘要】 目的 通过符合线路SPECT显像探讨肺部良性病变中18F 脱氧葡萄糖 (FDG)的摄取情况。方法 用双探头符合线路SPECT显像对肺部病变患者进行检查 ,观察各种病变摄取18F FDG的情况及其影像特征。结果 ① 2 8例肺结核患者中 ,19例 (6 8% )显像阴性 ,9例 (32 % )显像阳性 ,其靶/非靶 (T/N)值为 1 7± 1 2 ,而肺癌的T/N值为 4 1± 2 4,两者差异有显著性。显像阳性的 9例结核菌素 (PPD)皮肤试验红斑平均直径为 16 2 (12~ 2 2 )mm ,显像阴性的 7例为 8 6 (0~ 15 )mm ,两者差异有显著性。② 8例结节病中 5例显像阳性 ,为新发现的活动期病例 ;3例显像阴性 ,为经治疗好转者。③炎症患者 18例 ,其中隐球菌病、支原体肺炎、霉菌病、机化性肺炎、肺脓肿及细菌性肺炎各 1例显像阳性。结论 肺良性病变18F FDG显像也会产生阳性。对显像特征进行分析能提高对肺癌诊断的特异性 ,也为诊治良性病变提供一些新思路。

【Abstract】 Objective To study the uptake of the 18 F FDG in the benign pulmonary diseases with dual head SPECT coincidence detection system Methods Scanning were performed with dual head SPECT coincidence detection system for patients with pulmonary diseases,the uptake and the imaging characteristic of the diseases were analysed Results ①In 28 tuberculosis (TB) patients,19 cases with a negative imaging(68%,19/28),whereas 9 cases with a positive result(32%,9/28) The T/N value of the TB is 1 7±1 2,but the T/N of the lung cancer is 4 1±2 4,significantly different from them In the skin PPD test,9 cases with positive scans showed a 16 2(12~22) mm diameter red spot, but 7 cases of negative scans with a 8 6(0~15) mm diameter, both also have a significant difference ②Out of the 8 patients suffered from sarcoidosis,among them 5 active stage with positive scans,whereas another 3 remission cases with negative results ③In 18 inflammationary cases,positive imagings were showed in 6 patients with cryptococcosis,mycoplasma pneumonia,mycosis,organized pneumonia, lung abscess and bacteria pneumonia Conclusions In some benign pulmoary diseases, 18 F FDG imaging can be positive also Analysing the characteristic of the imaging could rise specificity in lung cancer and also give some new clues to treatment of these benign pulmonary diseases

  • 【文献出处】 中华核医学杂志 ,Chinese Journal of Nuclear Mdeicine , 编辑部邮箱 ,2001年01期
  • 【分类号】R817
  • 【被引频次】34
  • 【下载频次】66
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