【摘要】 目的　探讨血清铁代谢对乙型肝炎肝损伤的影响。方法　对收治的１０３例乙型肝炎患者按临床分型，观察铁代谢血清学指标血清铁蛋白、转铁蛋白、血清铁、总铁结合力与乙型肝炎肝损伤的关系。结果　血清铁蛋白、转铁蛋白、血清铁和总铁结合、乙型肝炎肝损伤相关。其中血清铁蛋白、血清铁随肝损伤加重而增加，转铁蛋白、总铁结合力随肝损伤加重而减少。结论　铁负荷过重可能协助ＨＢＶ加重肝损伤，因此检测铁代谢指标可以对乙型肝炎的治疗和预后作出评价。更多还原

【Abstract】 Objective To study the effect of iron metabolism on patients with hepatitis B. Methods Hemoglobin (Hb), serum ferritin (SF), transferrin (TRF), serum iron (SI), and total iron binding capacity (TIBC) were detected in 103 patients with hepatitis B and 20 healthy adults. Results The severer the hepatocyte damage was, the higher the SF, SI and the lower the Hb, TRF, and TIBC were. Furthermore, it seems more obvious among fulminant hepatitis and liver cirrhosis. Conclusions The overload of iron may enhance the hepatocyte damage induced by HBV. Therefore, to detect serum markers of iron metabolism is helpful to evaluate curative effect and prognosis of hepatitis B.更多还原