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31例中国人主要器官组织中42种元素浓度和含量研究

Concentrations and contents of 42 elements in main organs and tissues for 31 cases of Chinese man\

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【作者】 诸洪达陈如松王继先王松君田伟之高俊全王耐芬尹协瑜王珂石磊刘国栋

【Author】 ZHU Hongda,CHEN Rusong,WANG Jixian,et al.Institute of Radiation Medicine,Chinese Academy of Medical Sciences and Peking Union Medical College,Tianjin 300192,China\;

【机构】 中国医学科学院中国协和医科大学放射医学研究所中国辐射防护研究院长春科技大学中国原子能科学研究院中国预防医学科学院营养与食品卫生研究所北京医科大学公共卫生学院白求恩医

【摘要】 目的 测定中国成年男子主要器官组织中元素浓度和估算其含量 ,为确定中国参考人相应参数提供依据 ,为微量元素和健康关系研究提供我国当前资料。方法 在我国不同膳食类型的 4省市 (河北、山西、上海和四川 )采集 31例急死正常成年男子尸体肌肉、肋骨、肝、肾、肺和甲状腺样品 ,采用NAA、ICP MS、ICP AES、多种AAS技术和必要质控措施共测定 42种元素浓度 ,并按中国参考人器官组织重量估算了这些元素相应含量。结果 获得了 31例中国成年男子甲状腺中I、其他 5种器官组织中 40种元素和肋骨中Li的浓度及相应器官组织含量估算值。结论 本研究除更新了我国 15种元素相应资料外 ,首次获得 2 7种元素在这些器官组织中浓度和含量资料 ,为确定中国和亚洲参考人相应参数提供较为系统的依据。还就我国本次结果与近年国内文献值和对ICRP参考人相应参数最新国际估算值的比较 ,元素在这些器官组织中浓度的相对分布和地区差异进行了讨论。

【Abstract】 Objective\ To determine elemental concentrations in main organs and tissues of Chinese adult man and to estimate their organ and tissue contents in order to provide bases for development of relevant parameters for the Chinese Reference Man and related current data in China for research on relationship between trace elements and health. Methods\ Muscle,rib,liver,kidney,lung and thyroid samples in autopsy from 31 subjects died suddenly,who were healthy and normal before death,were collected from 4 provinces or citics with different dietary types in China (Hebei,Shanxi,Shanghai and Sichuan),The concentrations of 42 elements were analyzed by using NAA,ICP\|MS,ICP\|AES,several AAS techniques and necessary QC measures.With uses of the relevant organ or tissue weights for Chinese Reference Man,their contents were estimated. Results\ The concentrations of I in thyroid, 40 elements in other 5 organs or tissues and Li in rib for these Chinese adult men and their organ or tissue contents were obtained. Conclusion\ Besides updating the relevant data of 15 elements,this research also obtained data on concentrations and their contents of other 27 elements in the organs and tissues for the first time in China.The results provide quite systematic bases for developing the parameters of Chinese or Asian Reference Man.The results were compared with recent reference data of China and the new estimated values for theses parameters of ICRP Reference Man in literature,and relative distributions of elemental concentration and their regional differences were discussed.\;

【关键词】 中国人元素器官和组织浓度含量
【Key words】 Chinese man\ Element\ Organ and tissue\ Concentration\ Content
【基金】 国家自然科学基金!资助项目 (395 70 2 34);IAEA协作研究基金!项目 (8918/RI)
  • 【文献出处】 中华放射医学与防护杂志 ,Chinese Journal of Radiation Mediation and Protection , 编辑部邮箱 ,2001年01期
  • 【分类号】R341
  • 【被引频次】18
  • 【下载频次】130
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