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超常规剂量碘油超选择栓塞肝动脉治疗原发性肝癌

Superselective TAE with Hypernormal Dosage Iodized Oil in Treatment of Primary Hepatic Carcinoma

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【作者】 刘福全岳振东徐建国漆德芳蔺武杜伟生

【Author】 Liu Fuquan Yue Zhendong Xu Jianguo et al Department of Interventional Radiology, Beijing General Railway Hospital, Beijing

【机构】 北京铁路总医院介入科!北京市 100038白求恩医科大学第一临床学院北京铁路总医院消化内科北京铁路总医院肿瘤科

【摘要】 目的:探讨应用超常规剂量碘油超选择栓塞肝动脉治疗原发性肝癌的疗效。方法:1987年8月~1999年12月12年间167例原发性肝癌,应用常规导管或球囊导管超选择至肿瘤供血动脉,阻断其血流,使注射碘油时不产生逆流。将全部动脉肿瘤血管、病变周围正常的小动脉及肝实质和门静脉分支栓塞。结果:栓塞全部动脉肿瘤血管、病变周围正常的小动脉及肝实质167例,门静脉分支栓塞109例。1、2、3、4、5年生存率分别为98.8%(165/167)、79.9%(107/134)、48.0%(47/98)、36.6%(26/71)、25.5%(12/47)。没有严重并发症发生。结论:应用超常规剂量碘油超选择栓塞肝动脉治疗原发性肝癌效果良好,安全。

【Abstract】 Objective: To evaluate the efficacy of superselective transarterial embolization (TAE) with ultranormal dosage iodized oil in the treatment of primary hepatic carcinoma. Methods: Superselective TAE with ultranormal dosage iodized oil was performed on 167 patients with primary hepatic carcinoma. Two different catheters (a common catheter and a balloon catheter) were inserted into the blood supply artery of the tumor and the ultranormal iodized oil was injected to embolize all the blood supplying arteries, the perifocal arterioles and the branches of portal vein. The ballon was inflated to avoid the retrograde flow of blood. Results: The tumor blood supply arteries and all the perifocal normal arterioles were embolized in 167 cases and the portal vein branches were embolized in 109 cases. The 1-,2-, 3-, 4-, and 5-year survival rates of these patients were 98.8%, 79.9%,48.0%,36.6%,23.4% respectively. No serious complication or liver damage was found. Conclusion: Superselective TAE with hypernormal dosage iodized oil is effective for primary hepatic carcinoma.

  • 【文献出处】 中国肿瘤临床 ,Chinese Journal of Clinical Oncology , 编辑部邮箱 ,2001年04期
  • 【分类号】R735.7
  • 【被引频次】8
  • 【下载频次】35
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