【摘要】 目的　为了寻找一种灵敏、可靠的诊断方法 ,鉴别妇科疾病患者的腹水良恶性。方法　对 80例妇科疾病患者腹水的唾液酸水平 (SA)、铜 /锌比值 (CZR)及部分微量元素采用 75 1分光光度计和 30 30型原子吸收分光光度计进行测定。结果　结果表明卵巢癌患者腹水中SA水平和CZR明显高于宫颈癌和妇科良性疾病 ,差异显著 ,分别P <0 .0 1 ,并呈高度的线性关系。同时卵巢癌和宫颈癌患者腹水中锌和钙明显低于良性疾病组 ,差异显著 ,分别P <0 .0 1。结果还表明如以SA31mg/dl和CZR1 .1 0为界值对卵巢癌的诊断阳性率为 71 %和 5 5 %。 结论　腹水中SA和CZR的测定对鉴别妇科良恶性肿瘤有重要的临床价值 ,同时对探讨卵巢癌的发病因素提供重要线索更多还原

【Abstract】 Objective In order to explore the sensitive reliable dignostic method to identify gynecologic benign and malignant illness in asites.Methods The ascitic levels of sialic acid (SA) and Copper(Cu),Zinc (Zn),Calcium(Ca),Manganese(Mn) and Cu/Zn ratio in 80 paitents with cervical or ovarian cancer,benign gynecology diseases were determined by atomic aborption spectrophotometry(AAS).Results The results showed that SA and Cu/Zn ratio in ascites were significantly higher in patients with ovarian cancer than that with cervical cancer and benign illness,(P<0.01,respectively).Ascitic levels of Zn were lower in patients with ovarian and cervical cancer than that benign illness.The result also showed a cutoff SA value of 31mg/dl having a postive predictive rate of 71% and a cutoff Cu/Zn ratio value of 1.10 havng a postive predictive rate of 55% between ovarian cancer and benign illness.Conclusions These findings suggest that combined detection of ascites SA level and Cu/Zn ratio may be used as differentiative test in gynecologic bengn and malignant illness. [更多还原