【摘要】 目的 :分析甘油在体外的溶血特性。方法 :将正常人的红细胞加入到含不同浓度甘油的溶液中 ,在不同时间后测定剩余的红细胞数量 ,计算溶血的程度。结果 :在 0 .9%氯化钠和 5 %葡萄糖等渗液中 ,浓度 4 0 %以下的甘油无溶血作用 ,80 %甘油有溶血作用。在蒸馏水中 ,2 0 %甘油能短暂对抗蒸馏水引起的溶血作用 ,在 0 .3%氯化钠和 1.7%葡萄糖低渗液中 ,10 %和2 0 %甘油可对抗低渗溶液引起的溶血作用。结论 :甘油在体内的溶血作用可能是输入大剂量甘油引起肾脏损伤所致 ,而不是在输注时甘油与血液接触所致更多还原

【Abstract】 OBJECTIVE Side effect induced by iv infusion glycerol is hemolysis. Where hemolysis is because of catalysis of red cell and infused glycerol or other cause. METHODS Hence speciality of hemolysis of glycerol were studied in vitro. RESULTS There are no hemolysis in 0.9% NaCl and 5% glucose solution with 0～40% glycerol, but hemolysis occurred in them with 80% glycerol. 20% glycerol can antagonize hemolysis induced by distilled water in 1～2 min and 10%～20% glycerol can antagonize hemolysis induced by 0.3% NaCl and 1.7% glucose. CONCLUSIONS According to experimental result, may be hemolysis in vivo is due to renal damage induced by a lot of infused glycerol.更多还原