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电荷转移络合分光光度法测定吡拉西坦片含量
Determination of piracetam tablets by charge transfer complex spectrophotometry
【摘要】 目的:建立用电荷转移络合分光光度法测定吡拉西坦片含量的方法。方法:利用碘与吡拉西坦在二氯乙烷中形成荷移络合物,在227.2 nm波长处测定吡拉西坦片的 含量。结果:平均回收率为99.57%,RSD为1.24%,在4~220 μg·ml-1浓度范围内线性良 好,r=0.9998。结论:电荷转移络合分光光度法可简便、快速、准确地检测片剂中吡拉西坦的含量。
【Abstract】 OBJECTIVE To establish an accurate method to determine piracetam in tablet by c harge transfer complex spectrophotometry method. METHODS Piracetam reacted with iodine in dichloroethane forming a charge transfer comp lex,it can be quantitatively determined by spectrophotometric methode at 227.2 nm. RESULTS The arerage recovery was 99.6% and RSD=1.2%.The linear range was 4~22 0 μg·ml-1, r =0.9998. CONCLUSIONS The method can be used to determine the concentration of piracetam in tablet s imply,rapidly and accurately.
【Key words】 piracetam; spectrophotometry; iodine; charge transfer complex;
- 【文献出处】 中国医院药学杂志 ,Chinese Journal of Hospital Pharmacy , 编辑部邮箱 ,2001年10期
- 【分类号】R927.2
- 【被引频次】7
- 【下载频次】70