【摘要】 目的 通过对9年来安徽省麻疹发病年龄变化的分析,探讨其影响因素,为加速麻疹控制和调整免疫策略提供参考依据。方法 对1991-1999年麻疹流行病学和实验室资料进行分析,用ELISA法检测麻疹血清IgM和血凝抑制实验方法检测麻疹血清IgG抗体。结果 5-9岁组儿童麻疹发病构成占第一位,0～14岁儿童麻疹发病占81.91％-90.46％,麻疹发病年龄组后移,以学龄儿童为主,≥15岁人群1991年构成为9.44％,1999年为18.06％,强化免疫前暴发病例以5～9岁为主,1999年后以10～14岁为主。强化免疫前麻疹IgG抗体GMT为16.79±3.10,强化免疫后GMT、为44.77±2.25。结论 安徽省麻疹发病属于小年龄组模式,为加速麻疹控制,应进一步落实第二剂次MV的免疫,适时开展后续式MV强化免疫,以预防和控制麻疹暴发。更多还原

【Abstract】 Objective To provide factors and reference to the strategy adjustments for accelerating measles control and measles immunization.Methods The data of measles epidemiology and lab were analyzed through testing measles IgM antibody with ELISA and measles IgG antibody with HI.Results Measles cases among the children aged 5-9 years occupied the first position within 9 years. Measles cases in the children aged 10 - 14 years occupied from 81.91 % to 90.46%, most of them were students. Measles cases of people over 15 years accounted for 9.44% in 1991, 18.06% in 1999.The outbreak cases were dominated by the children aged 5 -9 years before MV Immunization campaign, by the children aged 10 - 14 years after the campaign.The GMTs of measles IgG antibody were 16.79±3.10, 44.77±2.25 before and after the campaign.Conclusions Measles takes place in the children of 0 - 14 yeare (Young Children Mode) in Anhui. We should pay more attention to the second MV immunization, and conduct MV follow - up immunization campaign and prevent measles outbreak.更多还原