【摘要】 目的 :探讨反流性食管炎 (RE)与幽门螺杆菌 (HP)感染的关系。方法 :将内镜诊断的 10 12例RE患者 ,依据HP检测结果分为阳性组和阴性组 ,按Tytagat分级进行严重程度比较。结果 :10 12例RE的HP感染率为71.8% ,Ⅲ～Ⅴ级的中重度RE检出率HP阳性组为 31.5 % (2 2 9/ 72 7) ,HP阴性组为 38.9% (111/ 2 85 ) ,两组比较有显著性差异 (P <0 .0 5 )。结论 :本地区RE患者的HP感染率较高 ,HP阴性者RE病变程度较重 ,显示HP感染可能对RE发病起保护作用更多还原

【Abstract】 Objective:To study association between helicobacter pylori (HP) infection and endoscopic degrees of reflux esophagitis (RE).Methods:1012 patients with endoscopically verified RE grades Ⅰ～Ⅴ(Tytagat) were divided into HP positive and HP negative groups,and the endoscopic degrees of two groups were analyzed.Results:Hp positive rate was as high as 71.8% in the total population analyzed.The percentage of patients with moderate or severe RE was higher in Hp negative group than in Hp positive group.Conclusions:The percentage of Hp infection is quite high among the patients with RE,and Hp positive rate correlate negatively with pathohistologic severity of RE.The therapeutic intervention and cure of HP may cause RE to be severe.更多还原