【摘要】 目的　探讨 2型糖尿病与活动性巨细胞病毒 (CMV)感染的关系。方法　应用PCR技术和ELISA法分别检测 47例 2型糖尿病病人血清中CMVDNA和CMV IgM。以CMVDNA(或 )CMV IgM阳性为活动性CMV感染诊断指标。结果　PCR技术和ELISA法检测结果具有高度一致性 (P <0 0 0 1)。 2型糖尿病病人活动性CMV感染率 (5 3 19%)显著高于对照组 (2 1 88%) (P <0 0 1) ,且活动性感染的病人中病程长于 6个月者占 72 %。血糖水平较高的病人活动性CMV感染率与血糖水平较低者比较差异有显著性意义 (P <0 0 5 )。结论　 2型糖尿病病人中存在较高的再发感染 ,这可能与 2型糖尿病发病有关。更多还原

【Abstract】 Objective To find out the relations between type 2 diabetes mellitus and active cytomegalovirus(CMV) infection.Methods HCMV DNA and CMV-IgM in sera from 47 type 2 diabetic patients were respectively detected by polymerase reaction (PCR) and ELISA.Patients with positive CMV DNA and (or) CMV-IgM was diagnosed as active CMV infection.Results There was a high correlation between PCR and ELISA in determining HCMV infection (P<0.001).The active CMV infection rate of type 2 diabetic patients was significantly higher than that of the controls (P<0.01),and 72% patients with active CMV infection had a course of disease more than 6 months.The active CMV infection rate of type 2 diabetic patients with higher blood sugar was much higher than that of those with lower blood sugar (P<0.05).Conclusion There existed a higher re-infection of CMN in type 2 diabetic patients,which was possibly related to the pathogenesis of type 2 diabetes mellitus.更多还原