【摘要】 目的　探讨产妇与新生儿弓形虫感染的有关危险因素。方法　采用整群抽样的方法共选取住院分娩的产妇 2 84例及其新生儿 2 84例 ,采集产妇静脉血 3ml(分娩前 )及其新生儿脐血 3ml,并进行相应的流行病学个案调查 ;用ELISA法一次性检测弓形虫循环抗原CAg、弓形虫特异性IgG和IgM抗体。结果　产妇阳性 15例 ,产妇总感染率为 5 2 8% ;新生儿阳性 5例 ,新生儿总感染率为 1 76 % ;产妇与动物 (猫、狗、鸡、鸭等 )密切接触史与其新生儿弓形虫感染有非常显著性的统计学联系 (OR =2 8 39,OR95 %CI为 3 5 8～ 10 2 32 ,P <0 0 1)。结论　从优生优育的角度出发非常有必要加强对妊娠期妇女的检测和管理。更多还原

【Abstract】 Objective To identify the risk factors of toxoplasma gondii infection in maternal women and newborn infants.Methods An epidemiological study on the risk factors of toxoplasma gondii infection was conducted during 1996-1997 in two hospitals of Ningbo. This was carried out by random cluster sampling techniques of target population and clinical survey (including ELISA ). During this study a total of 284 maternal women and their newborn infants (also 284) were selected and examined.Results The overall prevalence rates of toxoplasmosis among maternal women and their newborn infants were 5.28% (15/284) and 1.76% (15/284), respectively. Meanwhile, there was marked significant difference in the history of closely contact with animals in maternal women and toxoplasma gondii infection of their newborn infants ( OR =28.39, OR 95% CI 3.58～102.32, P <0.01). In addition, other risk factors of toxoplasma gondii infection in maternal women and their newborn infants were analyzed and discussed.Conclusion Based on the study findings,sero-epidemiologic survey in pregnant women showed an important significance in better child-bearing.更多还原