【摘要】 目的　了解HIV/AIDS高危人群特异性免疫状况 ,为干预对策提供信息。方法　整群抽取桑拿浴服务人员外周血196例 ,采用流式细胞术观察T淋巴细胞免疫表型。结果　WBC总数 <5 0× 10 9/L和LYM <1 2× 10 9/L分别为2 0 85 %和 18 40 %。LYM1 2～ 1 5× 10 9/L的CD+3 和CD+4 为 10 72个 / μl和 35 3个 / μl,极显著高于LYM <1 2× 10 9/L的690个 / μl和 2 44个 / μl(P均 <0 0 1)。但CD+3 ,CD+4 /CD+8为63% ,32 7%和 1 34 ,显著低于后者 (68 2 % ,35 1%和 1 48,P<0 0 5和P均 <0 0 1)。结论　本市服务行业人员免疫功能不健全 ,CD+4 普遍低下的现象应受关注。LYM <1 2× 10 9/L的CD+3 % ,CD+4 %和CD+4 /CD+8反而高于LYM≥ 1 2× 10 9/L的现象可能与免疫调节的应激功能有关更多还原

【Abstract】 Objective To understand the conditions of specific immunity in the HIV/AIDS high risk group,and to provide information to the strategy of the intervention.Methods To get 196 blood samples by using cluster sampling in sauna bath.To observe T lymphocyte immunophenotype with flow cytometer.Results The WBC total <5 0×10 9/L and LYM<1 2×10 9/L were 20 85% and 18 40% separately.The CD + 3 and CD + 4 were 1072/μl and 353/μl in people with LYM 1 2～1 5×10 9/L,which was obviously higher than 690/μl and 244/μl in those with LYM<1 2×10 9/L(P av <0 01).But CD + 3,CD + 4 and CD + 4/CD + 8 were 63%,32 7% and 1.34 separately,which was obviously lower than the latter(68.2%,35 1% and 1 48,P<0 05 and P av <0 01).Conclusion The immuno function in service workers in Shenzhen was not sound.The CD + 4 was generally low,which should be focused on.The fact that the CD + 3,CD + 4 and CD + 4/CD + 8 in people with LYM<1 2×10 9/L was higher than those with LYM≥1 2×10 9/L may relate to the stress function of the immuno regulation.更多还原