【摘要】 目的　了解辽宁省正常人群不同年龄组抗麻疹病毒抗体免疫水平。方法　 1999年采集全省 6个市地 14个区县不同年龄组 6 93份血清 ,使用B95A细胞以微量细胞培养方法测定抗麻疹病毒中和抗体。结果　 2～ 4岁 ,2 0～ 2 5岁组抗体阳性率为 94% ,其它年龄组均在 96 %以上。但是 2～ 4岁GMT开始下降 ,6～ 8、9～ 11岁组最低 ,这两个年龄组发病率也最高。此结果与 1999年麻疹发病率吻合。结论　提示儿童在 2岁和 5岁时应各进行 1次麻疹疫苗接种 ;鉴于 1999年 13～ 15岁组麻疹发病率是 0 6 / 10万的情况 ,建议如果条件允许 ,14岁以下年龄应每隔 5～ 6年普遍再接种 1次麻疹疫苗。更多还原

【Abstract】 Objective To know neutralization antibody level against measles virus(MV)of health people in the Liaoning province.Methods 693 serum samples of different age groups were collected in 14 counties and districts in 6 areas of the Liaoning province in 1999.Neutralization antibody was detected by cell micro culture using B95A cell.Results The results indicated that positive rate was 94% in the 2～4 and 20～25 years old groups and in other groups was more than 96%,but GMT was lower in the 2～4 years old group,lowest in 6～8 and 9～11 years old groups.Which conformed to the measles incidence in 1999,the incidence was the highest in the 6～8 and 9～11 years old groups.Conclusion It points out that children of 2 and 5 years old would be vaccinated by MV vaccine again in order to increase antibody against MV.It is best for children who are unden 14 years old being vaccinated again every 5～6 years if possiblee,because measles incidence was 0.6/100,000 in the 13～15 years old group in 1999 in Liaoning province.更多还原