【摘要】 目的　探讨结节性筋膜炎的临床和病理特征。方法　对 2 0 1例结节性筋膜炎会诊病例进行总结分析并结合文献进行讨论。结果　结节性筋膜炎的好发部位为上肢 ,尤其是前臂 ;发病高峰年龄为 2 0～ 2 9岁 ;大多数(82 4% )病变最大径小于 3cm ;病程大多数 (81 6 % )不超过 3个月。具诊断意义的 4个主要的组织学特征为细胞整体排列方式呈长束状S形轻度弯曲 ;小裂隙状空间 ;血管外红细胞及黏液样间质基质。常常可以见到正常核分裂象。结论　诊断结节性筋膜炎应紧密结合其快速生长的临床特点 ,抓住 4个主要的组织学特征及常见正常核分裂象的特点。注意防止过度诊断肉瘤更多还原

【Abstract】 Objective To investigate the clinical and pathological features of nodular fasciits. Method Histopathological changes of nodular fasciitis in HE stained sections were analyzed in 201 consultation cases with review of the literature. Results The lesion usually occurred in young adults in their third decade,most often at the arm,especially the forearm.Most lesions(82 4%) were less than 3 cm in maximal dimension and most duration(81 6%) of the lesions was less than 3 months.There were four main diagnostic histological features including the overall pattern of S shaped whorls of myofibroblasts,and thin cleft like spaces between myofibroblasts,the extravasated red cells lying within the clefts and the interstitial mucoid material.Normal mitotic figures were nearly always present. Conclusions It is important for us to make a diagnosis in combination of the clinical feature of rapid growth with four main histological changes as well as normal mitotic figure.Special attention should be paid to prevent overdiagnosis as sarcomas.更多还原