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络泰粉针剂对脑缺血的保护作用

Protective Effects of Luotai Injection Powder on Cerebral Ischemia

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【作者】 李辉张华明方春生杨再康王成军赖泳刘晓波

【Author】 LI Hui, ZHANG Hua ming, FANG Chun sheng, YANG Zai kang, WANG Cheng jun, LAI Yong, LIU Xiao bo (Dali Medical College, Dali 671000, China)

【机构】 大理医学院药理学教研室!云南大理671000大理医学院药理学教研室!云南

【摘要】 目的 :研究络泰粉针剂对脑缺血的保护作用。方法 :用结扎颈总动脉合并降压法制备脑缺血模型研究络泰粉针剂对动物脑缺血的影响。结果 :络泰粉针剂 (6 0mg/kg ,12 0mg/kg)可使缺血大鼠的脑含水量、脑毛细血管通透性、脑组织缺血损伤程度下降 ;络泰粉针剂 (12 0mg/kg)还能使小鼠耐缺氧能力明显提高。 结论 :络泰粉针剂对脑缺血有保护作用

【Abstract】 Objective:To study the protecting effects of Luotai Injection Powder on cerebral ischemia.Methods: The protecting effects of Luotai Injection Powder on cerebral ischemia were studied on animal models of cerebral ischemia induced by ligaturing bilateral common carotid artery and decressing blood pressure. Results:Luotai Injection Powder (at doses of iv. 60mg/kg and 120mg/kg) significantly decreased the water content, capillary permeability and ischemia injury in brain of rats. In addition, it significantly increased the tolerance in mice at a dose of iv. 120mg/kg. Conclusions: Luotai Injction Powder has a protective effect on acute cerebral ischemia

  • 【文献出处】 中成药 ,Chinese Traditional Patent Medicine , 编辑部邮箱 ,2001年06期
  • 【分类号】R285.5
  • 【被引频次】16
  • 【下载频次】80
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