【摘要】 目的 :自行组方、研制肾康胶囊 ,观察其治疗隐匿性肾小球肾炎的临床疗效及副作用。方法 :肾康胶囊由黄狗肾、鳖甲、肾炎草等中草药按现代制药技术制成。隐匿性肾小球肾炎 6 0例 ,随机分 2组 ,对照组有蛋白尿者给予雷公藤多甙片口服 ,有伴随症状者给予支持对症治疗 ;肾康胶囊组口服肾康胶囊 5粒 ,每日 3次 ,有伴随症状者给予支持对症治疗。两组疗程均为 3个月。两组患者药前后观察 2 4时尿蛋白定量、血清总蛋白 (TP)、白蛋白 (Al)、1时尿红细胞排泄率(1huRBCer)、血肌酐和钠。结果 :肾康胶囊能显著减轻隐匿性肾小球肾炎蛋白尿 ,从而提高TP、AL水平、并可显著减少1huRBCer。肾康胶囊使用过程中无不良反应。结论 :使用肾康胶囊治疗隐匿性肾小球肾炎是有效的方法且无明显毒副作用。更多还原

【Abstract】 Objective:Shenkang was prescribed and prepared by our own hospital and its clinical effect and side effect for treating latent glomerulonephritis(LGN) were observed. Methods: Shenkang was composed of dog’s penis Carapar Trionycis、nephritis herb and so on and prepared by the modern pharmaceutical technology. 60 cases with LGN were divided into the control group(30 cases) and the Shenkang group(30 cases) at random. Patients with protein uria in the control group were treated with the tablet of multiglycoside of Radix Tripterygii Wilfordi and patients with accompanied symptom were treated by the supportive expectant treatment. Patients in the Shenkang Capsule group were treated with it, 5 tables each time, 3 times a day and patients with accompanied symptom were also treated by the supportive expectant treatment. The treatment courses of two groups were all 3 months. 24 hour protein uria quantity、 serum total protein(TP)、 albumin(Al)、 1 hour urine red blood cell excreting rate(1huRBCer)、 serum creatinine and sodium before and after the treatment were observed. Results: Shenkang Capsule can significantly lower protein uria of LGN so as to raise the levels of TP and Al and reduce 1huRBCer. There was no side effect in the course of using Shenkang Capsule. Conclusion: Shenkang Capsule is effective for LGN.更多还原