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左旋氧氟沙星治疗单纯性淋病合并衣原体和/或支原体感染的临床观察

Clinical Comparing Study of the Tfficacy of the Treatment of Uncomplicated Gonorrhea Co-infected Chlamydia trachomatis and Mycoplasma by Levofloxacin or Cetriaxone Pulse Doxycycline

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【作者】 赖维张玉清朱国兴黄怀球陈荣章

【Author】 LAI Wei,ZHANG Yu qing,ZHU Guo xing,et al Department of Dermatology and Venereology,The Third Affiliated Hospital,Sun Yat Sen University of Medical Sciences.Guangzhou 510630,China

【机构】 中山医科大学附属第三医院皮肤性病科!广东广州510630

【摘要】 目的 比较两种治疗方案 (左旋氧氟沙星 2 0 0mg 2次 /d共 7天与头孢三嗪 2 5 0mg单剂量肌注加强力霉素 10 0mg 2次 /d共 7天 )治疗单纯性淋病合并衣原体和 /或支原体感染各 3 0例的有效性和安全性。 方法 采用随机、开放、对照研究 ,试验组及对照组各 3 0例。结果 两组病例的痊愈率分别为 83 .3 3 %和 86.67% ,总有效率为 90 %和 93 .3 3 % ,差异无显著性 (P >0 .0 5 ) ;副反应发生率分别为 3 .3 3 %和 16.67% ,差异有显著性 (P <0 .0 5 )。结论 口服左旋氧氟沙星方案可作为治疗淋病合并衣原体和 /或支原体感染的治疗方法之一。

【Abstract】 Objective To compare the efficacy and safety of two regimens in the treatment of uncomplicated gonorrhae co infected with chlamydia/mycoplsma.Methods A randomized,open,and parallel control clinical trial.Group A was treated with Levofloxacin 200mg,two times daily for 7 days;Group B was treated with Ceftriaxone 250mg,intramascularly for single dose plus Doxycline 100mg,two times daily for 7days.Results Each group had 30 patients,the efficacy rate for group A and group B was 90% and 93.3% respectively,no significant difference was found between two groups( P >0.05);the occurring rate of adverse effects was 3.33% and 16.67% respectively,a significant difference existed between the two groups(P<0.05).Conclusion Levofloxacin can be used in treatment for uncomplicated gonorrhae co infected with chlamydia/mycoplsma effectively and safety.

  • 【文献出处】 中国皮肤性病学杂志 ,The Chinese Journal of Dermatovenereology , 编辑部邮箱 ,2001年01期
  • 【分类号】R759.2
  • 【被引频次】11
  • 【下载频次】53
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