【摘要】 目的:探讨我院真菌感染与应用抗菌药物的关系,促进临床合理应用抗菌药物。方法:对32例院内真菌感染的病例进行回顾性分析结果:所有病例均应用抗菌药物,其中预防性用药11例(34.4％)。主要药物是第三代的头孢菌素类和氟喹诺酮类;换药频繁且多为联合用药;累计应用品种多,平均为(7.2±3.6)种;应用时间长,平均为(33.0±20.1)天。医院真菌感染主要部位是呼吸系统,主要菌种是白色念珠菌,抗真菌治疗不规范。结论:院内真菌感染最主要的危险因素是不合理应用抗菌药物,应予以足够的重视。更多还原

【Abstract】 OBJECTIVE: To study the relation between nosocomial fungous infections and use of antimicrobials, so as to promote rational use of antimicrobials. METHODS: 32 cases of nosocomial fungous infections were analysed retrospectively. RESULTS: All cases have been administrated with antimicrobials for a long period, the average period of use of antimicrobials was 33.0d±20.1d. 11 cascs(34. 4% ) were given antimicrobials for prevention. The third generation of cephalosporins and quinolones were the main drugs to be used. Antimicrobials were changed frequently, and mostly were used in combination. The accumulative kinds of antimicrobials used were manifold with an average of 7.2 ±3.6 kind. Antifungal treatment was not standardized. CONCLUSION: The main cause of nosocomial fungous infections is irrational use of antimicrobials. We should pay attention to nosocomial fungous infections.更多还原