【摘要】 目的 :探讨硫酸镁辅助治疗顽固性癫的剂量、方法及疗效。方法 :治疗组 72例 ,用 2 5 %硫酸镁 10mL静脉滴注 ,或用 16.5 %硫酸镁 10mL口服。对照组 3 6例给予常规抗癫药物 ,卡马西平或苯妥英钠加苯巴比妥或氯硝西泮加用γ 氨基丁酸等治疗。结果 :治疗组有效率 87.5 % ,对照组有效率 44.4% ,两组比较经统计学分析P <0 .0 1,差异极显著。结论 :硫酸镁联合一线抗癫药治疗顽固性癫的方法简单易行 ,具有良好效果更多还原

【Abstract】 Objective: To determine the dosage, method and effectiveness of using magnesium sulfate for treating the intractable epilepsy. Methods: 72 cases were allocated to treatment group and 36 to control group. For those in the treatment group, either 10 mL of 25% MgSO 4 was administered by intravenous drip or 10 mL of 16.5% MgSO 4 by oral intak e once per day, in addition to the use of the commonly used antiepilepsy drugs. For those in the control group, the commonly used antiepilepsy drugs such as teg retol, sodium phenytoin, luminal or γ-Aminobutyric Acid were employed. Results: The improvement rate in the treatment group was 87.50% , higher than that (44.44%) in the control group (P<0.01). Conc lusion: Using magnesium sulfate in conjunction with the antiepilepsy drugs is a simple yet effective regime for the treatment of the intractable epil epsy.更多还原