【摘要】 本文了解紫外线照射库血后及其储存不同时期血液理化指标的变化,来探讨紫外线照射对库血质量的影响以进行安全可行性研究。方法:采用成对血标本对照,进行紫外线照射前后及其储存72小时,120小时后测定其血常规,血浆K+、Na+、Cl-离子,血气,红细胞脆性和红细胞ATP酶活力的变化,进行组间比较和组内比较。并经过3500u血液临床应用观察输血后输血反应情况,并与对照组相比,紫外线照射对库血理化指标无影响;但可使淋巴细胞的转化率从（70.57±10.66）％下降到（48.42±10.12）％（p<0.001）;经.紫外线照射后3500u全血临床应用,非溶血性输血反应率仅为0.5％。因此我们认为:紫外线照射库血可降低淋巴细胞增殖反应能力,使非溶血性输血反应降低,其安全,简便,可行,可以推广使用。更多还原

【Abstract】 Objectives: To understand changes of the physicochemical index of banked blood during different storage periods after ultraviolet irradiation and to explore the affects on the quality of banked blood resulted in ultraviolet irradiation.Methods: Paired blood samples are used in contrast. Changes to blood routine, blood ion, blood gas, erythrocyte fragility and erythrocyte ATP Enzyme activity are tested 72h,120h, pre and post ultraviolet irradiation separately, Comparison is made between groups and within in one groups. Blood transfusion reaction is observed during clinical of 3500u blood. Results: To compare with the contrast group, there is no change physicochemical index of banded blood after ultraviolet irradiation; But its can reduce the rale of lymphocytes transformation from (70.57±10.66)% to (48.42±10.12)% (P<0.001);Febrile nonhemolytic transfusion reactions is only 0.5% in the clinical use of 3500u ultraviolet irradiation banked blood. Conclusions: Ultraviolet irradiation can decrease the response of lymphocytes to PHA and reduce febrile nonhemolytic transfusion reactions. It is safe, simple and practical and can be used widely.更多还原