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宁波地区收缴滥用药物的成分分析

DETERMINATION OF THE COMPONENTS AND IMPURITIES OF ILLICIT DRUGS SEIZED IN NINGBO BY GC-MS

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【作者】 张亚海张建兵吴开封周文华杨国栋

【Author】 ZHANG Yahai1, ZHANG Jianbing1, WU Kaifeng2, ZHOU Wenhua1, YANG Guodong11(Ningbo Institute of Microcirculation and Henbane, Ningbo, 315010) 2(Ningbo Public Security Bureau, Ningbo,315010)

【机构】 宁波市微循环与莨菪类药研究所宁波市公安局宁波市微循环与莨菪类药研究所 宁波315010宁波315010

【摘要】 目的·· :确定宁波地区收缴滥用药物的主要成分及其掺杂物的种类并对收缴海洛因的含量进行详细分析。方法··:采用气相色谱 -质谱联用法 ,检测2000年度宁波地区收缴的滥用药物的主要成分及其掺杂物。结果··:2000年度宁波地区收缴的滥用药物共送检136份 ,其中检出海洛因123份、氯胺酮5份、曲马朵4份、甲基苯丙胺1份、艾司唑仑1份、大麻1份、三唑仑1份。收缴的滥用药物海洛因的含量差异明显 ,平均含量为35.13 %±s22.63%(n=123) ;海洛因中的掺杂物主要有咖啡因 ,检出率为70.73% (87例)、对乙酰氨基酚 ,检出率为43.90 %(54例)、普鲁卡因 ,检出率为11.38 %(14例)等。结论··:宁波地区收缴的滥用药物以海洛因为主 ,呈现多元化状态 ,氯胺酮滥用上升速度迅猛。海洛因中掺杂物种类繁多。海洛因中乙酰可待因与单乙酰吗啡之间的比值与海洛因的含量有相关性

【Abstract】 Objective: To determine the main components and impurities of illicit drugs in Ningbo. Method: Seized drugs were determined by gas chromatography-mass spectrometry (GC-MS). Result: Totally 136 samples of illicit drugs seized in the year 2000 were analyzed. 123 samples were detected as heroin, 5 ketamine, 4 tramadol, 1 methamphetamine, 1 estazolam, 1 cannabis, 1 triazolam. The contents of heroin composed in the drug varied significantly, with an average of 35.13%±s 22.63%(n=123). The heroin contents (20.84%±s 21.63%,n=60)in samples with low acetylcodeine/monoactylemorphine ratio (<1) were lower than those (48.73±s 23.57%,n=63) with high ratio (>1). The main impurities in heroin samples were caffeine (87 samples),paracetamol (54 samples), procaine (14 samples).Conclusion: Heroin is the main illicit drug in Ningbo and ketamine is increased rapidly. The acetylcodaine/monoactylemorphine ratio of heroin samples is related to the contents of heroin.

【关键词】 气质联用海洛因氯胺酮甲基苯丙胺掺杂物
【Key words】 GC-MSillicit drugheroinketaminemethamphetaminetramadol
  • 【文献出处】 中国药物依赖性杂志 ,Chinese Journal of Drug Dependence , 编辑部邮箱 ,2001年04期
  • 【分类号】R914
  • 【被引频次】16
  • 【下载频次】88
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