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济泰片联合洛非西定治疗海洛因依赖的临床疗效观察

CLINICAL EFFECT OF JITAI TABLET COMBINED WITH LOFEXIDINE IN THE TREATMENT OF HEROIN DEPENDENCE

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【作者】 熊建国; 肖早香; 李军; 秦德胜; 闵明山; 杨建辉; 王艳红; 晏灵; 舒秋丽;

【Author】 XIONG Jianguo, XIAO Zhaoxiang, LI Jun, QIN Desheng, MIN Mingshan,YANG Jianhui, WANG Yanhong, YAN Ling, SHU Qiuli(Yichang Compulsory Detoxification Institute, Yichang ,443001)

【机构】 宜昌市强制戒毒所; 宜昌市强制戒毒所 宜昌; 443001; 宜昌;

【摘要】 目的··:探索戒毒疗效好、不造成新的药物成瘾 ,且经济的脱毒方案。方法·· :将60例海洛因依赖者分成A、B两组组 ,A组给予济泰片联合洛非西定脱毒,B组单纯使用小剂量美沙酮脱毒 ,对照观察两组的脱毒疗效。结果·· :在控制戒断症状方面 ,A组与B组比较无显著性差异(P<0.05) ,但A组不良反应轻微。B组有17例停用美沙酮后有索药行为。两药合用 ,济泰片用量减少。结论··:济泰片联合洛非西定组临床疗效可靠 ,且无成瘾性 ,副作用少 ,价格低,值得推广应用

【Abstract】 Objective: To explore effective and economic pharmaceutical therapy without inducing new drug dependence. Method: 60 heroin addicts were divided into two groups (Group A and Group B ) and treated with Jitai tablet combined with lofexidine (Group A) and methadone only (Group B). The result was compared. Result: In controlling withdrawal symptoms there was no significant difference (P<0.05) between the two groups. However, Group A experienced fewer and mild adverse drug effects. The cost in Group A was reduced. 17 patients in Group B sought for methadone after administration stopped. Conclusion: Jitai tablet combined with lofexidine can treat heroin dependence effectively with fewer adverse effects. No new dependence is produced. It is fairly cheaper.

  • 【文献出处】 中国药物依赖性杂志 ,Chinese Journal of Drug Dependence , 编辑部邮箱 ,2001年04期
  • 【分类号】R749.6
  • 【被引频次】19
  • 【下载频次】88
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