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喉返神经吻合术治疗喉外展麻痹的实验研究

Experimental study on the recurrent laryngeal nerve anastomosis for the treatment of laryngeal abductor paralysis

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【作者】 何晓光孙俊俞志成张德芳王文慧

【Author】 HE Xiaoguang,SUN Jun,YU Zhichen,et al.The First Affiliated Hospital of Kunming Medical College,Kunming(650032)

【机构】 昆明医学院第一附属医院耳鼻咽喉科!云南昆明650032昆明医学院人体解剖系!昆明650031昆明医学院电生理室昆明医学院第二附属医院肌电图室!昆明650101

【摘要】 目的 探讨喉麻痹的神经吻合治疗术效果。方法 造成犬单侧喉返神经干完全性损伤 ,同时切断其喉内收肌支干 ,即行同期膈神经—喉返神经神显微神经吻合术 ,造成膈神经对同侧喉返神经外展肌支的单一支配。对正常、神经切断后立即及神经吻合术后 4月环杓后肌进行肌电功能学及形态学检查。结果 神经吻合术后 4月 ,环杓后肌肌电活动恢复 ,运动神经终板体系已开始形成 ,但要达到完全正常水平 ,仍需一定恢复时间。结论 喉返神经吻合术能有效治疗喉外展麻痹。

【Abstract】 Objective To explore the effect of the reinnervation operation for the treatment of the laryngeal paralysis.Methods The unilateral recurrent laryngeal nerve(RLN)and its adducent branch were cutted at the same time.The nervous reinnervation between the phrenic nerve and the RLN was then realized on purpose to make the phrenic nerve purely innervating the posterior cricoarytenoid muscle (PCA).The morphology and electromyography examination were realized at the different time of the experiment.Results Four months after the operation,the morphology and electromyography examination on the PCA showed that the new nerve-ending system began to recover.It still needed some time to reach to normal level.Conclusions The nervous anastomosis of the recurrent laryngeal nerve is effective for the treatment of laryngeal abductor paralysis.

【基金】 云南省科委应用基础研究基金资助课题 (94C0 5 0Q)
  • 【文献出处】 云南医药 ,Medicine and Pharmacy of Yunnan , 编辑部邮箱 ,2001年03期
  • 【分类号】R767.91
  • 【被引频次】2
  • 【下载频次】25
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