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梅笠草提取物的抗炎及镇痛作用

Experimental study of extract of Meilicao on anti-inflammation and analgesic effects

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【作者】 孙连平; 纪英; 李洪兰; 张红英;

【Author】 SUN Lian-ping 1,JI Ying 2,LI Hong-lan 3,ZHANG Hong-ying 1 (1.Department of Pharmacology,Yanbian University College of Medicine, Yanji 133000, Jilin,China;2.The Preparation Department,Affiliated Hospital of Yanbian University College of Medicine, Ya

【机构】 延边大学医学院药理学教研室; 延边大学医学院附属医院制剂室; 延吉市医院药剂室; 延边大学医学院药理学教研室 吉林; 延吉133000; 吉林; 延吉133000;

【摘要】 [目的 ]探讨梅笠草提取物的抗炎及镇痛作用 .[方法 ]采用巴豆油所致小鼠耳壳肿胀的方法 ,测定耳片的肿胀度 ;用冰醋酸所致小鼠的扭体次数 ,测定小鼠的扭体反应次数 .[结果 ]梅笠草对巴豆油所致小鼠耳壳肿胀有抑制作用 ,与对照组相比有显著性差异 ;同时能减少冰醋酸所致小鼠的扭体次数 ,与对照组相比有显著性差异 .[结论 ]梅笠草提取物具有一定的抗急性炎症和抗镇痛作用

【Abstract】 OBJECTIVE To research and inquire into abstractor of Meilicao on anti-inflammation and analgesic effects. METHODS Measuring swelling degrees of ear flaps induced by croton oil,measuring number of times of mice twisting body response induced by acetic acid. RESULTS Meilicao significantly inhibited swelling induced by croton oil in the ear of mice. There is significant difference between Meilicao group and control group.Meanwhile, significantly reduced frequency of twisting body response induced by acetic acid ,there is extraordinarily significant difference. CONCLUSION Abstractor of Meilicao has certain antagonize accuse inflammation and analgesic affect.

【关键词】 镇痛; 植物,药用; 巴豆油; 醋酸类; 小鼠;
【Key words】 analgesia; plants, medicinal; croton oil; acetic acids; mice;
  • 【文献出处】 延边大学医学学报 ,Journal of Medical Sciecnce Yanbian University , 编辑部邮箱 ,2001年04期
  • 【分类号】R285.5
  • 【被引频次】4
  • 【下载频次】62
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