【摘要】 目的 :评价左氧氟沙星片剂治疗慢性阻塞性肺疾病 (COPD)病人下呼吸道细菌感染的有效性、安全性及临床实用性。方法 :30例COPD急性加重期门诊病人 [男性 18例 ,女性 12例 ,年龄 56a±s10a ( 4 1～ 80a) ]给予左氧氟沙星片剂 2 0 0mg ,3～ 4d后改为 10 0mg ,均po ,bid ,总疗程 7～ 9d。结果 :COPD急性加重期门诊病人经左氧氟沙星治疗后 ,痊愈 14例 ( 4 7% ) ,显效 8例 ( 2 7% ) ,改善 7例( 2 3% ) ,治愈率为 74 % ,细菌消除率 92 % ,药物不良反应少而轻。结论 :左氧氟沙星片剂治疗COPD急性加重期门诊病人下呼吸道常见细菌感染有效、安全、疗程短更多还原

【Abstract】 AIM: To evaluate the efficacy,safety and practicality of levofloxacin tablets in treating lower respiratory tract bacterial infection in patients with acute exacerbation of chronic obstructive pulmonary disease(COPD). METHODS:Thirty COPD outpatients with lower respiratory tract bacterial infection (M 18,F 12;age 56 a± s 10 a) were treated with levofloxacin 200 mg, po , bid for 3 4 d,followed by 100 mg po ,bid for 4～5 d,total treatment course was 7 9 d. RESULTS: The effective rate was 97%,the cure rate was 74% and the bacterial eradication rate was 92%.Adverse reaction were rare and mild.CONCLUSION:Levofloxacin is an effective and safe antibiotic in the treatment of lower respiratory tract infection in outpatients with acute exacerbation of COPD,and the therapeutic course is short.更多还原