【摘要】 目的 :了解羟氯喹在眼科的不良反应及其发生率。方法 :选择较长期 (疗程≥ 6mo)服用羟氯喹的病人 39例 ,进行眼科检查包括一些特殊的眼功能检查。结果 :39例中 3例 (8% )出现视野范围缩小 ,其中 1例伴有视敏度降低。这 3例服用羟氧喹累积剂量均大于 10 0g。结论 :本观察显示羟氯喹眼科不良反应的发生可能与累积剂量有关 ,表现为视野改变和视敏度降低。更多还原

【Abstract】 AIM: To study the adverse reactions of hydroxychloroquine (HCQ) in ophthalmology. METHODS: Thirty nine patients treated with HCQ for more than six months were performed ophthalmic examinations including some specifie retinal function tests. RESULTS: There were 3 patients (8%) who presented the visual fields was minified. The visual acuity of one patient was decreased. The cumulative doses of HCQ were more than 100 g in this three patients. CONCLUSION: The adverse reactions of HCQ in ophthalmology are related with the cumulative doses of HCQ. The expression is that the visual fields and visual acuity are decreased.更多还原