【摘要】 目的:研究检测急性白血病患者血浆D-二聚体水平的临床意义。方法:用酶联免疫吸附试验(ELISA)检测42例初治急性白血病患者(观察组)治疗前后、30名健康人(对照组)以及部分复发病例血浆中的D-二聚体水平。结果:观察组血浆D-二聚体水平明显高于对照组;治疗有效组血浆D-二聚体水平明显低于无效组(P<0.05);有效组10例患者的血浆D-二聚体水平随着病情的缓解与复发呈动态变化。结论:动态检测急性白血病患者血浆D-二聚体水平对判断疗效及预测复发具有一定的临床意义。更多还原

【Abstract】 Objective: To investigate the alteration and clinical significance of D dimer levels in acute leukemia. Methods: Levels of D dimer were measured by ELISA in 30 normal subjects and 42 acute leukemia patients before and after treatment. Results: Levels of D dimer of acute leukemia patients before treatment were higher than that of normal subjects. Levels of D dimer in effective treatment group were higher than that of unresponsive group. Significant difference in D dimer levels between the two groups was found. In part patients levels of D dimer changed with progress of disease. Conclusion: Monitoring D dimer serum level may be helpful in judging treatment effect and relapse.更多还原