【摘要】 目的 :总结幼年类风湿性关节炎的诊治经验。方法 :对 86例幼年类风湿性关节炎的临床表现与免疫学测定进行了分析。结果 :诊断为全身型 1 7例 ,占 1 9 8% ,多关节型 31例 ,占 36 % ,少关节型 38例 ,占 4 4 2 % ,免疫学测定表明 ,活动期出现免疫球蛋白IgA增高 1 6例 ,占 1 9 2 % ,IgG增高 2 7例 ,占 31 5 % ,IgM增高 1 2例 ,占 1 3 7% ,补体C3 增高 1 5例 ,占1 7 5 % ,C4 增高 33例 ,占 38 0 % ,CIC增高 80例 ,占 92 9% ,RF阳性 1 6例 ,占 1 8 9% ,ANA阳性 1 6例 ,占 1 9 0 % ,HLA -B2 7阳性 5 2例 ,占 6 0 0 %。结论 :根据上述资料 ,按病情轻重 ,除应用非甾类抗炎药物外 ,加用强的松、甲氨蝶呤 ,同时辅以理疗 ,大关节封闭等更多还原

【Abstract】 Objective: To discuss the diagnosis and treatment of juvenile rheumatoid arthritis(JRA). Methods:Clinical and immunological analysis was performed in 86 cases with JRA. Results: Among all cases, 17 patients (19 8%) were systemic-onset disease, 31patients(36%)polyarticular-onset disease, and 38patients(44.2%) pauciarticular-onset disease. The results of immunological measurement showed that the rise in IGA was 19.2%, IgG 31.5%,IgM 13.7%, complement C3 17.5%, C4 38.0%,CIC 92.2% and the positive rate of RF was 18.9%, ANA 19.0%, HLA-B27 60.0%.Conlusions:Based on the patient’s condition,in addition to using the non-steroidal anti-inflammatory agents, block therapy for joints and physiotherapy,selected application of Prednisone and Methotrexate can be beneficial.更多还原