【摘要】 目的 :探讨青年乳腺癌的临床及病理特点。方法 :分析了 1 984年 1月至 1 999年 3月收治的 35岁以下青年乳腺癌病人的临床资料。结果 :1 32例中 ,病程最短者为 3日 ,最长者为 1 2 0月 ,其中 1个月以内者 2 8例 ,3个月以内者 2 7例 ,6个月内者 2 8例 ,1 2个月内者 2 9例 ,2 4个月内者 1 1例 ,2 4个月以上者 9例 ,病程 1年以内者占 85 0 % ,平均 1 0 1月 ;病期 0期 4例 ,Ⅰ期 1 7例 ,Ⅱ期 74例 ,Ⅲ期 32例 ,Ⅳ期 5例 ;病理分型以浸润性癌为主 ,占 96 2 % ,其中浸润性导管癌为 31 1 % ,单纯癌为 5 6 8% ,69例有腋下淋巴结转移 ,占 5 2 3% ;有 8例为妊娠、哺乳期患者 ;1 32例全部行手术治疗 ,获随访 1 0 7例 ,术后 3年生存率为 86 6% ,5年生存率为 77 3%。结论 :青年乳腺癌病程较长 ,浸润性癌为主 ,淋巴转移率高以及合并妊娠、哺乳 ,肿瘤分期晚 ,预后不良是其特点。更多还原

【Abstract】 Objective:To study the clinical pathologic features of breast cancer in young adults.Methods:To analyze the clinical data of 132 young adults with breast cancer,aged less than 35 years and hospitalized from Jan.1984 to March,1999.Results:Of the 132 cases,the shortest illness course was 3 days while the longest was 120 months,including 28 within one month,27 within 3 months,28 within 6 months,29 within 12 months,11 within 24months and 9 over 24 months.The patients with the illness course within one year accounted for 86.6%,with the average of 10.1 months.Four cases were in stage 0,17 in stage Ⅰ,74 in stage Ⅱ,32 in stage Ⅲ and 5 in stage Ⅳ respectively.The pathologic classification showed the dominance of infiltration cancer,accounting for 96.2%,including 31.1% infiltrating duct cancer and 56.7% cancer simplex.Sixty nine cases had the axillary lymph node metastasis,accounting for 52.3%,8 cases were in the pregnaccy or breast-feeding periods.All 132 cases were surgically treated and the post-operative follow-up showed that the 3-and 5-year survival rates were 86.6% and 77.3% respectively.Conclusion:The breast cancers in young adults had longer course and were mainly the infiltrating malignancies.The patients were usually featured by the poor prognosis because of being usually in pregnancy or in breast brecding period,and cancer in advanced stage with higher lymph metastasis rate.更多还原