【摘要】 目的　探讨丝裂霉素 C在泪囊鼻腔吻合术中的应用及效果。方法　将 92例 10 5眼慢性泪囊炎随机分为 MMC组 48例 5 5眼和对照组 44例 5 0眼 ,MMC组术中应用 0 .4g· L- 1 MMC,对照组未用 MMC,术后平均随访 2 9m o。结果　手术成功率 :MMC组为98.0 8% ,对照组为 82 .6 1% (P<0 .0 5 )。吻合口开通率 :MMC组为 10 0 % ,对照组为82 .6 1% (P<0 .0 1)。前后瓣膜愈合时间 :MMC组为 7.86 d± 2 .75 d,对照组为 7.2 2 d±2 .2 3d(P>0 .0 5 )。吻合口出血发生率 :MMC组为 3.6 2 % ,对照组为 2 % .结论　 MMC可作为治疗慢性泪囊炎的一种安全、简单、有效的辅助措施 ,明显提高手术成功率更多还原

【Abstract】 Objective To probeinto the application and effect of mitomycin C(MMC) to dacryocystorhinostomy Methods The chronic dacryocystisis,92 cases(105 eyes)were performed with the same level dacryocystorhinostomy,randomly divided into two groups:MMC group,48 cases(55 eyes) given MMC 0 4g·L -1 Control group,44 cases (50 eyes) without MMC The average period of postoperative following up was 29 months ResultsThe successful rates of remote operations: 98 08% in MMC group,82 61%( P <0 05) in the control group The percentage of anastomotic stoma open:100% in MMC group,82 61%( P <0 01) in the control group Healing period of anterior and posterior valve:7 86d±2 75 d in MMC group and 7 22d±2 23d( P >0 05) in the control group The bleeding ratio of anastomotic stoma:3.62% in MMC group, 2% in the control group.Conclusion MMC can be used as one of safe ,simple ,effective and auxiliary measures to treat chronic dacrocystisis,which can notably enhance the successful rates of operations更多还原