【摘要】 目的 :了解虫草菌多糖保健粉的大鼠胚胎毒性和对胎儿的致畸性。方法 :应用传统致畸试验。结果 :各剂量组胎鼠毒性和畸形与阴性对照组比较无显著性差异 ,而给予极高剂量 (达 5 0 0 0 mg/ kg. bw )时 ,孕鼠体重增重显著性低于阴性对照组。结论 :虫草菌多糖保健粉对孕鼠体重增重有一定的影响 ,无胚胎毒性和致畸性更多还原

【Abstract】 Objective:The embryoxicity and teratogenicity studies of Cordyceps sinensis(Berk.) Sacc amylose powder were conducted in rats by traditional teratogenicity test.Result:The frequency of terates and the embryotoxicity of the fetus in each dose group were not significantly different as compared with negative control group.However,in very high dose(up to 5000mg/kg.bw),the growth of body weight in gestation of rats were significant lower than negative control.Conclusion:The Cordyceps sinensis(Berk.) Sacc amylose powder had slight effect on the body weight growth of pregnant rats,and possesses no embryotoxicity and teratogenicity.更多还原