节点文献
超声促进4,4-二取代-2-苯基-2-噁唑啉-5-酮的水解
Hydrolysis of 4,4-disubstituted-2-phenyl-2-oxazolin-5-one prometed by ultrasonic irradiation
【摘要】 目的 :碱性水解 4,4 二取代 2 苯基 2 口恶唑啉 5 酮 1。方法 :用超声波促进 1水解。结果 :1在超声波作用下很快水解 ,生成N 苯甲酰 2 ,2 二取代 2 氨基乙酸 ,没有超声辐照 ,室温水解需搅拌 2 4h ,而有超声辐照 ,反应仅需 15min。结论 :超声波能有效促进 1的碱性水解。
【Abstract】 OBJECTIVE:To hydrolyze of 4,4 disubstituted 2 phenyl 2 oxazolin 5 one 1 in base.METHOD:Using ultrasonic irradiation to promote the hydrolysis of 1.RESULTS:1 hydrolyze very quickly with the presence of ultrasonic irradiation and N benzoyl α,α disubstituted glycines were obtained. In room temperature the reaction was completed within 15 min while it had to stir for 24 h without ultrasonic irradiation.CONCLUSION:Ultrasonic irradiation promotes hydrolysis of 1 in base effectively.
【关键词】 超声波;
氨基酸;
噁唑啉5-酮;
水解;
【Key words】 ultrasonic irradiation; amino acid; oxazolin-5-one; hydrolysis;
【Key words】 ultrasonic irradiation; amino acid; oxazolin-5-one; hydrolysis;
- 【文献出处】 中国现代应用药学 ,Chinese Journal of Modern Applied Pharmacy , 编辑部邮箱 ,2001年01期
- 【分类号】O626
- 【被引频次】4
- 【下载频次】83