【摘要】 目的　检测非刺激和刺激情况下 ,正常人全唾液和纯腮腺液中透明质酸的含量 ,以探讨正常人唾液中透明质酸的含量和了解唾液中透明质酸在伤口愈合中的作用。方法　采用酶联免疫吸附试验法 (ELISA) ,对 2 0名健康成人唾液进行测定。结果　透明质酸的含量依次为 :非刺激下全唾液 (36 9.89ng /ml) ,刺激下全唾液 (15 8.6 1ng /ml) ,非刺激下腮腺液 (95 .80ng /ml) ,刺激下腮腺液 (79.2 0ng /ml)。 结论　①唾液中含有透明质酸 ;②不同类型的唾液透明质酸的含量有较大差异 ;③透明质酸在唾液中的高浓度可能有助于唾液的伤口愈合、口腔粘膜的保护和润滑作用。更多还原

【Abstract】 Objective This study was to determine the concentration of whole saliva and pure parotid saliva under unstimulated and stimulated conditions, and to understand the role that hyaluronic acid plays in intraoral wound healing.It was established of the baseline concentrations of hyaluronic acid in normal adult human pure patotid saliva and mixed whole saliva.Methods The hyaluronic acid concentration was evaluated by means of ELISA.Results The concentrations of hyaluronic acid were as follows: unstimulated whole saliva(369.89ng /ml), stimulated whole saliva(158.61ng /ml), unstimulated parotid saliva(95.80ng /ml), stimulatid parotid saliva(79.20ng /ml).Conclusion There are great variations in the levels of hyaluronic acid of human saliva depending on the type of saliva and the collected conditions.The hyaluronic acid may be contributed to the healing properties of saliva, assist in protecting the oral mucosa and add to the lubricating properties of saliva.更多还原