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多发性脑梗死患者高级神经功能障碍与P300对比研究

The comparision between high nerve dysfunction and P300 in multiple cerebral infarction

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【作者】 任惠朱成宝刘彬

【Author】 REN Hui,ZHU Cheng- bao,LIU Bin.The First Affiliated Hospital, Kunming Medical College, Kunming 650032,China

【机构】 昆明医学院第一附属医院!云南昆明650032云南省牟定县人民医院

【摘要】 目的探讨多发性脑梗死( MI)患者高级神经功能障碍与事件相关电位( ERPs)间的相关性。方法对 34例 MI患者进行智商( IQ)、记忆商( MQ)、失认症及 ERPs检查,并与 31例年龄、性别和利手相匹配的正常人比较。结果 MI患者的 N2及 P3波峰潜伏期( PL)较对照组显著延长( P< 0.01), P3波幅显著降低( P< 0.05); IQ、 MQ与 N2及 P3PL呈显著负相关( P< 0.05)。结论 ERPs检查与传统神经心理检查方法相结合,能较准确地观察疾病对高级神经功能的影响。

【Abstract】 Objective To study the relationship between high nerve dysfunction and P300 in patients with multiple cerebral infarction(MI).Method Intelligence quotient (IQ),memory quotient (MQ),recognizition and ERPs of 34 patients was examined with MI, and compared with those of 31 normal subjects mached with age,sex,handedness.Result The peak latencies (PL) of N2 and P3 of the MI patients were significantly delayed (P< 0.01), and the amplitude of P3 was significantly decreased (P< 0.05) than that of control group. There was significant negative relation (P< 0.05) between IQ or MQ and P3PL.Conclusion Combining ERPs and traditional neuropsychogical examination, We can exactly identify the impact of condition on the high nerve dysfunction.

【基金】 云南省科委青年科学基金资助 (Q137)
  • 【文献出处】 现代康复 ,Modern Rehabilitation , 编辑部邮箱 ,2001年13期
  • 【分类号】R743.33
  • 【被引频次】9
  • 【下载频次】57
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