【摘要】 目的测定中年大鼠血脂含量的变化。方法 40只雄性 SD大鼠随机分为四组：对照组、服药组、运动组和服药＋运动组。后二组进行游泳训练 8周（ 5d/周， 1.5h/d）。结果（ 1）服药＋运动组体重明显下降。（ 2）与对照组相比，服药组、运动组和服药＋运动组血清 TC、 TG、 LDL－ C和动脉粥样硬化指数 AI降低 ,HDL－ C提高；服药＋运动组 HDL－ C提高有极显著差异（ P< 0.01）。（ 3）与对照组相比，后三组 APOB－ 100极显著降低 (P< 0.01) ;服药组、服药＋运动组 APOAI和 APOA/APOB比值显著提高 (P< 0.05)；服药＋运动组和运动组相比， APOB－ 100降低和 APOAI、 APOA/APOB提高有显著差异（ P< 0.05）。结论中药紫丹蓝和运动训练在调节脂代谢及抗动脉粥样硬化方面具有显著作用。更多还原

【Abstract】 Objective The purpose of this investigation was to measure the changes of Seuumlipid levels in rats.Method Forty male SD rats were radomly divided into four groups:control,drug,exercise and diug＋ exercise.The exercise and drug＋ exercise performed swimming exercise training progrm(5 days/week,1.5 hour/day)a 8weeks.Result (1)The weights of the rats were significantly lower in drug＋ exercise groups:(2)TC,TG,LDL－ c and AL levels were decreased and HDL－ c increased in drug,exercise and drug＋ exercise groups;in drug＋ exercise group,HDL－ c was obviously increased(P< 0.01)as compared with control group.(3)ApoB－ 100 levels significantly decreased in drug,exercise and drug＋ exercise groups(P< 0.01);ApoAI and ApoA/ApoB increased in drug and drug＋ exercise Groups(P< 0.05);ApoB－ 100 decreased and ApoAI,ApoA/ApoB,increased in drug＋ exercise group(P< 0.05).Conclusion There results suggeasted that ZiDanLan and exercise have a significant effect on controlling weight and regulating the metabolism of serum lipids and may be beneficial to antiatherosclerosis.更多还原