【摘要】 用免疫组织化学 SP法结合葡萄糖氧化酶 - DAB-硫酸镍铵呈色法 ,对正常成年大鼠室管膜上 IFN- γ的特征和分布进行了研究。结果表明 :IFN- γ免疫反应阳性细胞分布于大鼠侧脑室壁、第三脑室壁、中脑导水管、第四脑室壁的室管膜中。其中侧脑室、第三脑室、第四脑室壁上存在有伸长细胞 ,发出基突伸向周围灰质。提示 IFN-γ可能作为一种新的脑神经肽存在于室管膜中 ,参与脑 -脑脊液回路的调节更多还原

【Abstract】 Using immunohistochemical SP method and visualized with glucose oxidase- DAB- nickel method examine the distribution and characteristics of Interferon- γ(IFN- γ) in normol adultrat ependyma. The results showed that IFN-γ immunoreactive production existed in the wall ofthe lateral ventricle(LV) , the third ventricle(V3) ,the aqueductof midbrain(MA) and the wall ofthe forth ventricle(V4) .These cells belonged to tanycyes and situated in the ependyma of LV、V3、V4.Their basal processes extended into the central gray.The results suggest that IFN- γ may be a novel brain- gut peptide and modulate brain- CSF circuit.更多还原