【摘要】 随着反义核酸的发现及对其研究的深入 ,反义技术已被应用于生物基因调控的研究 ,并逐步应用于抗病毒及肿瘤、爱滋病等基因水平治疗等新兴药物的开发 .概述了反义核酸概念及作用机理 ,人工反义的设计、合成以及应用前景更多还原

【Abstract】 With the discovery of antisense nucleic acid and further research, antisense technique has been applied in the study of gene regulation, and progressively find its application in gene therapy comprising fighting virus, preventing and curing cancer & acquired immunity deficiency syndrom(AIDS), developing novel medicines, etc. This paper reviews the definition, action mechanism of antisense nucleic acid, as well as the design & synthesis of artificial antisense RNA and its prospect of utilization.更多还原