节点文献

姬松茸多糖的分离纯化及其对白血病细胞的抑制作用

Isolation and Purification of Polysaccharides from Agaricus blazei Murill and Its Inhibitory on Human Leukaemia Cell

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 沈爱英; 孙震; 刘平; 谷文英;

【Author】 SHEN Ai ying 1, SUN Zhen 2, LIU Ping 2, GU Wen ying 2 (1. Department of Biology, Suzhou University, Suzhou 215151, China; 2.School of Food Science and Technology, Wuxi University of Light Industry, Wuxi 214036,China)

【机构】 苏州大学生物系!江苏苏州215151; 无锡轻工大学食品学院!江苏无锡214036;

【摘要】 姬松茸子实体经热水提取 ,乙醇沉淀 ,DEAE -纤维素和SephadexG 2 0 0柱分离纯化 ,得ABP Ⅱ α和ABP Ⅱ β两种纯多糖。研究了两种多糖对体外人白血病细胞的抗癌作用 .结果表明 ,两种多糖对人白血病细胞均有不同程度的抑制作用 ,并与作用时间和作用剂量呈正相关 .

【Abstract】 Two polysaccharides, ABP Ⅱ α and ABP Ⅱ β, were isolated from the fruit bodies of Agaricus blazei Murill. They were further purified by DEAE cellulose and Sephadex G 200. The anti tumor activities of the two polysaccharides against leukaemia cell were studied by MTT method. The results showed that both of them had different degree of anti tumor activities . The results of the growth period test indicated that the inhibiting activities of ABP II α and ABP II β against leukaemia cell were positive correlation with reaction time and dose.

【关键词】 姬松茸; 多糖; 抗癌活性;
【Key words】 Agaricus blazei; polysaccharide; anti tumor activity;
  • 【文献出处】 无锡轻工大学学报 ,Journal of Wuxi University of Light Industry , 编辑部邮箱 ,2001年04期
  • 【分类号】Q539
  • 【被引频次】76
  • 【下载频次】346
节点文献中: 

本文链接的文献网络图示:

本文的引文网络