【摘要】 目的：评估立体核心活检在乳腺癌诊断中的意义。方法：１９９９年３月１５日～２０００年３月１５日，我院外科门诊应用意大利Ｇｉｏｔｔｏ乳腺诊断系统行高清晰乳腺Ｘ线摄影（ＨＩ－ＴＥＣＨ ｍａｍｍｏｇｒａｐｈｙ，ＨＴ－Ｍ）１８８８例，对其中符合：①临床扪及乳腺肿块，性质不明；②Ｘ线片发现肿块；③Ｘ线片上有多形性、集簇性微小钙化灶；④双侧摄片出现局限不对称、高密度区或结构畸形等适应证者，进行数字化局部处理（ｄｉｇｉｔａｌ ｓｐｏｔ ｉｍａｇｅ，ＤＳＩ）与Ｂａｒｄ １６Ｇ针立体核心活检（ｓｔｅｒｅｏｔａｃｔｉｃ ｃｏｒｅ ｎｅｅｄｌｅ ｂｉｏｐｓｙ，ＳＣＮＢ）１２２例，占ＨＴ－Ｍ总数的６．４６％。结果：诊断为乳腺癌（包括２例原位导管癌，１例早期导管浸润癌）５９例，全部手术证实；良性病变（包括乳腺增生、纤维腺瘤、导管乳头状瘤、囊腺瘤等）６３例，其中２３例为手术证实，４０例随诊中未发现癌变。在乳腺癌中，ＳＣＮＢ真阳性率为８９．８３％（５３／５９），假阴性率为１０．１７％（６／５９）；乳腺良性病变中ＳＣＮＢ无一例假阳性，故ＳＣＮＢ对乳腺良恶性病变的敏感性和特异性分别为８９．８３％和１００％，全部１２２例ＳＣＮＢ者均无并发症发生。结论：更多还原

【Abstract】 Objective: To explore the value of stereotactic core needle biopsy in diagnosing breast cancer.Me- thods: From March 15, 1999 to March 15, 2000, 1 888 patients were examined by Giltto’s HI-TECH Mam- mography(HT-M) in outpatient clinic. Among them, 122 underwent digital spot image(DSI) and sterotac- tic core needle biopsy(Bard’s needle 16G, SCNB). The indications of DSI and SCNB included: ①Palpable mass; ②A mass found on X-film; ③Pleomorphic cluster microcalcifications on X-film; ④Asymmetry as- sociated with architectural distortion or locally high density on X-film. Results: Fifty-nine cases of breast cancer were proved by pathologic examination(three were intraduct carcinomas in situ or early invasion). The true positive rate of SCNB was 89.83%(53/59) and false negative rate was 10.17%(6/59); Sixty-three ca- ses of benign lesions were proved by operations and follow-up. The sensitivity and specificity of SCNB for malignant tumor were 89.83% and 100% respectively. There was no complication in this group.Conclu- sions: A series of modern equipment including HT-M, DSI and SCNB is essential to gain the precise diag- nosis. Professional team consisted of general surgeons, surgical nurses(technicians) and pathologists should work together and manage the whole course to achieve optimal results.更多还原