【摘要】 目的 :研究大鼠幽门括约肌胆碱能神经元的特异性分布状态。方法 :采用 ACh E组织化学方法在冰冻切片和胃—幽门—十二指肠连续全层撕片上显示 ACh E阳性神经元成分。结果 :括约肌的解剖结构特异 ,于胃端侧与肠端侧括约肌肌层结构复杂 ,有较丰富的 ENS直接支配。括约肌的粘膜下层及肌层有富含胆碱能神经元的内源性小神经节和 ACh E阳性纤维网 ,尤以大弯侧最多。ACh E阳性神经丛的密度及丛内胞体数量 ,在与括约肌紧邻的胃和肠之间存在差异。结论 :幽门括约肌胆碱能神经元的特异性分布状态可能与其对括约肌舒缩的特异调控作用有关更多还原

【Abstract】 Objective: To investigate distribution of AChE-positive neurons in pyloric sphincter. Methods: Auerbach’s myenteric plexus(AMP) and Meissner’s submucos plexus(MSP) of pyloric sphincter were studiced by AChE histochemistry in cryostat section and whole-mount prepatation. Rusults: Anatomic structure of pyloric spincter is specific. There are large number of ENS in sphincter. There are AChE-positive neuronce between gaster and intestine next to sphincter in MSP and AMP of pyloric sphincter, large bent is the most. There is different in and plexus of AChE-positive, numbers of neuronal bodies. Conclusion: Specific distrbution of AChE positive neurons in pyloric sphinctermay be relevent to its specific function.更多还原