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正常和龋病牙髓中血管内皮细胞的免疫组化研究

Immunohistochemical Study on Endothelial Cells in Human Dental Pulp with Normal and Carious Teeth

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【作者】 王岷峰; 杨若愚; 吴丽更; 侯芝艳;

【Author】 WANG Minfeng.YANG Ruoyu.WU Ligeng.et al School of Stomatology, Tianjin Medical University, Tianjin 300070

【机构】 天津医科大学口腔医学院; 天津医科大学口腔医学院 300070; 300070;

【摘要】 目的:观察龋病发展进程中,血管内皮细胞对龋源性刺激的反应。方法:采用von Willebrand’s Factor标记正常和龋病牙髓中的血管内皮细胞,进行了定性和定量分析。结果:龋病牙髓中vWF阳性的血管增多,牙本质龋各组和正常组之间比较均有显著性差异(P<0.01)。结论:血管内皮细胞在维持牙髓自身稳定和修复中起重要作用。

【Abstract】 To observe the response of endothelial cells to the stimuli of dentinal tubule-derived caries during the development of caries. Methods: Immunohistochemical staining was performed with anti-vWF as the marker of endothelial cells in normal and carious dental pulp. The qualitative and quantitative analysis of the positive vessels was carried out. Results:The number of vWF-positive vessel increased in dental pulp of the carious teeth, and there was a significant difference between dentinal carious groups and the normal group (P<0.01). Conclusion:Endothelial cell plays an important role in hemostasis and repair of dental pulp.

【基金】 天津市自然科学基金
  • 【文献出处】 天津医药 ,Tianjing Medical Journal , 编辑部邮箱 ,2001年04期
  • 【分类号】R780.2
  • 【被引频次】1
  • 【下载频次】45
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